Faculty & Staff


Dr. Edward DonnayEd Donnay
Professor, Chair
Inorganic Chemistry

B.A. - University of St. Thomas 1996 (St. Paul, MN)
Ph.D. - Washington University 2002 (St. Louis, MO)

Office: 217 Science
Phone: 325-793-3878
e-mail: donnay.edward@mcm.edu

Family and Personal Interests:
Hello, my name is Edward Donnay and I was born and raised in Wadena, Minnesota. It is a small town of approximately 4500 people located in the center of the state. In addition to my parents who still reside in Wadena, I have two brothers, a niece, and a nephew that live in Minnesota. I have a third brother who is a Catholic priest with the Crosier order and he lives in their community in Phoenix, Arizona.

Outside of work I enjoy reading, cooking, watching TV, and playing strategy games. I am a long distance fan of Minnesota sports teams, particularly the Twins. When I exercise I play racquetball, walk and shoot hoops. My favorite TV shows are Mythbusters, Family Guy, Dirty Jobs, CSI, and The Daily Show.

Research Interests:
As a synthetic inorganic chemist I am interested in making new and unusual transition metal complexes. One area of study is the synthesis of ruthenium and chromium complexes that contain three diimine or polypyridyl ligands. The ability to fine tune the environment around the metal centers by changing the ligands will allow us to tailor the molecular properties to approach various problems.  For example these types of complexes have been proposed as possible anticancer agents through their use in photodynamic therapy (PDT).  In this respect, chromium compounds have an additional advantage due to the ability of the excited state to directly oxidize guanine, a DNA base, without oxygen being present.  However, chromium compounds are more difficult to prepare and study than the ruthenium alternatives. Furthermore, the delivery and binding of the transition metal complexes to DNA is still an area of intense investigation.

I am also interested in addressing synthetic problems or issues that are brought to my attention by colleagues inside academia or local industry. Collaboration and bringing multiple approaches to a problem is the best way to find innovative solutions.  The goal is to involve students in these projects to allow them to become familiar with current issues.

Teaching Interests:
In addition to teaching Inorganic and Physical Chemistry, my teaching duties usually include General Chemistry and Chemistry in Society (a course designed for non-majors).

Along with Dr. Veltkamp, we have revised the approach used to teach General Chemistry. We have switched to an inquiry-based approach with hands-on group activities replacing some or the entire traditional lecture format.  We continue to stress the importance of scientific writing and safety procedures while teaching the laboratory portion of the course. We also include more biochemical topics to better serve the interests of students who take the course.

As a consequence of the change in topics covered in General Chemistry, some material must be taught in other courses such as Inorganic Chemistry.  I am trying to develop a sophomore level course to include this material and complement the upper-level course already being taught and boost interest in this often “forgotten” area of chemistry.  This change would further align the curriculum to the one advocated by the American Chemical Society.

As mentioned above, I also teach Physical Chemistry and have worked to collaborate with the Advanced Laboratory class offered by the Physics Department. Working as a research team with people trained in different fields is an essential.




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Dr. Paul S. PyentaPaul Pyenta

Professor
Biochemistry

B.S. and B.A. - Wayne State University 1993 (Detroit MI)
Ph.D. - Cornell University 2000 (Ithaca NY)

Office: 216 Science
Phone: 325-793-3880
email: pyentap@mcm.edu

Research Interests:
Cancer cells have been shown to overexpress histone deacetylase (HDAC), an enzyme involved in protein expression (translation) and cellular division.  New inhibitors (HDACi's) targetting HDAC's may serve as new anti-cancer therapies.  In collaboration with Dr. Shin (organic chemistry, McM), we are developing, synthesizing, and assaying new molecules as such inhibitors.  Many molecules are derivatives of known inhibitor SAHA, and contain hydroxamic acid functional groups to act as zinc binding centers.  Other molecules target the portion of the ligand lying at the external part of the binding site.  Molecules are assayed using water soluble tetrazolium salt (WST-1) tests on cells lines such as MDA-MB-231 (triple negative breast cancer) and MCF-7.  This allows determination of effective concentraion (EC50) values for quick comparison between inhibitors. The binding of ligands to HDACs is also modeled in silica using vina autodock software.  Binding data can potentially predict ligand efficacies and correlate to in vivo assay results.

Teaching Interests:
Teaching is an honor and pleasure.  New methods of pedagogy are continually being developed, and an active teacher takes pleasure in "trying out" new ideas.  I enjoy teaching undergraduate classes including general chemistry, nursing chemistry, biochemistry, biophysical chemistry, and immunochemistry.  A favorite approach I employ is the flipped classroom.  This allows for time for my active learning and dynamic workshop-style approaches during classtime.





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Dr. Pamela VeltkampPam Veltkamp

Professor
Analytical Chemistry

B.A. - Dordt College 1984 (Sioux Center, IA)
Ph.D. - University of Colorado at Boulder 1991 (Boulder, CO)

Office: 222 Science
Phone: 325-793-3881
e-mail: veltkamp@mcm.edu

Research Interests:
My research focus is in Chemical Education. I am interested in finding and developing better ways to teach college-level chemistry, both in the classroom and in the laboratory.  This focus also includes studying how students approach a particular topic in chemistry and elucidating the errors that students may hold.  Such knowledge about the thought processes used by students can then be used to develop more effective ways of teaching the topic.

Teaching Interests:
I teach the general, analytical, and environmental course in the department.  These currently include General Chemistry I and II, Quantitative Chemical Analysis, Instrumental Analysis, and Environmental Chemistry.  I have been using Process Oriented Guided Inquiry (POGIL—see www.pogil.org) in General Chemistry and am beginning to apply this teaching method to other courses.  I am also involved in teaching Leadership in Science and Mathematics, a general education course that meets the requirement of the Leadership, Excellence, and Virtue portion of the general education curriculum.




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Dr. Hyunshun ShinHyunshun Shin

Professor Organic Chemistry

M.S., Drexel University 1998 (Philadelphia, PA)
Ph.D., Drexel University 2001 (Philadelphia, PA)
Postdoctoral Study: University of Pennsylvania 2001-2006 (Philadelphia, PA)

Office: 215 Science
Phone: 325-793-3879
e-mail:
shin.hyunshun@mcm.edu

 

RESEARCH INTERESTS: 

Our interests, a collaborative effort with other researchers across the country, is centered around the following aims:

--The design and synthesis of medicinal compounds using molecular docking models and investigating the structure-activity relationships (SAR) of metalloenzyme X-ray crystals, including histone deacetylases, beta-lactamases, and arginine biosynthesis (arginases and ornithine decarboxylases)
--The extraction of naturally bioactive agents from plants native to West Texas is associated with anti-cell proliferation, antimicrobial activity, and brain function mechanisms.
--The development of microwave-assisted synthetic methods to harness bioactive molecules in ways that are effective, efficient, and safe for the environment
--The investigation of toxicities of cosmetic ingredients chemical reactions before and after their formulation 

 

PERSONAL & TEACHING INTERESTS:

My focus in teaching aligns with my interests as well as applications associated with some of my research. Learning is a lifelong process; it does not begin and end within a formal classroom setting bounded by time limits. As such, I attempt to incorporate real-life challenges and opportunities for active learning into my classes. This kind of problem-solving approach helps students better understand and retain the principles and concepts that I am offering them. I also introduce research projects into my laboratory classes, such as the design and synthesis of new inhibitors targeting metalloenzymes to provide skills and practical knowledge students can carry with them into their future professions.






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Mr. Steve DavisSteve Davis


Laboratory Manager
Chemistry and Biology

B.S. - McMurry University 1998
Office: 218 Science
Phone: 325-793-4937
e-mail:davis.steve@mcm.edu

Being Laboratory Manager is one position on campus where routine rarely applies. Being directly involved with faculty from Chemistry and Biology, a working science background has been essential to help meet the needs of both faculty and students. My position at McMurry may involve setting up experiments, negotiating prices with vendors for equipment purchases, helping new faculty, supervising student workers, chemical/hazardous waste management, safety equipment inspection, working with contractors, working with different departments on campus, and greenhouse and plant care. I see the focus here at McMurry being on the success of the student and their educational endeavor. Knowing I had a part in their success is a personal benefit I get from my work.